So the first thing to do is to sign up at a bitcoin pool. The stickies in this bitcointalk section have links for the top 10 pools. The main differences between them are the payout models and the fees. If you just want to try things out, choose one of the most popular pools like Deepbit or BTC Guild. You can then try others, according to your needs. Now you need to install a miner. It has a simple interface, a drop down menu with a list of pre-configured pools and it is not difficult to setup. After you install the miner, you need to point it towards your pool. So select device you want to mine with (probably your FPGA/ASIC), enter the pool URL (if you don’t know what it is, check the FAQ/help section of your pool’s website) and your username/password.
Although I am a developer and love to customise my computer, I don’t like tweaking (though I am capable of :P) minor things. Few months ago, I tweaked every single thing on my laptop. Now, I want to focus on the work for which I started my laptop, instead of worrying about why the title bar is looking so small. This is the main reason I’ve switched to Ubuntu (Unity). Now, things just work, and I can focus more. Everyone is just accustomed to certain basic things. Once, my presentation in a hackathon got screwed because my laptop had KDE and I didn’t know how to mirror displays (which is by drag and drop in settings), and everyone knew GNOME settings, which has a button to click and go. I was on the stage and the person controlling my laptop couldn’t figure out, and that day I removed KDE.